About
This SPARQL endpoint contains Rhea reactions data (see statistics), and a snapshot of ChEBI data matching the Rhea release. It is free to access and supports the SPARQL 1.1 Standard.
The query timeout is 20 minutes. All triples are available in the default graph. There are two named graphs: <http://sparql.rhea-db.org/rhea> and <http://sparql.rhea-db.org/chebi>.

Documentation
See Rhea RDF diagrams.

Downloads
See Rhea FTP (rhea.rdf) and ChEBI FTP (chebi.owl).

Contact
See feedback form.
Examples
  1. Select all Rhea reactions (unspecified direction), with "Approved" status
  2. Select the number of approved reactions involving lipids (subclass of CHEBI:18059) based on the ChEBI ontology
  3. Select all approved reactions involving lipids (subclass of CHEBI:18059) based on the ChEBI ontology
  4. Select all approved reactions using CHEBI:29985 (L-glutamate) as small molecule participant
  5. Select all approved reactions using L-glutamine (CHEBI:29985) AND L-glutamate (CHEBI:58359) in different reaction sides
  6. Select all approved reactions annotated with a given Pubmed ID (2460092)
  7. Select all approved transport reactions
  8. Select all cross-references (to KEGG, MetaCyc, MACiE, ...) for a given reaction (RHEA:11932)
  9. Select all approved reactions linked to a given EC number (EC 1.1.1.353)
  10. Distribution of reactions according to the first level of enzyme classification (federated query)
  11. Select all compounds and count their occurence in Rhea reactions
  12. Select children of CHEBI:35179 (a 2-oxo carboxylate) in the ChEBI hierarchy (using rdfs:subClassOf), used in Rhea reactions or not
  13. Select all the descendants of CHEBI:35179 (a 2-oxo carboxylate) in the ChEBI hierarchy (using rdfs:subClassOf+), used in Rhea reactions or not
  14. Select children of CHEBI:35179 (a 2-oxo carboxylate) in the ChEBI hierarchy (using rdfs:subClassOf) used in Rhea reaction(s), and show the reaction(s)
  15. Select all the descendants of CHEBI:35179 (a 2-oxo carboxylate) in the ChEBI hierarchy (using rdfs:subClassOf+) used in Rhea reaction(s), and show the reaction(s)
  16. Select the child reaction(s) of a given reaction (RHEA:11628) in the Rhea hierarchy (using rdfs:subClassOf)
  17. Select the descendant reaction(s) of a given reaction (RHEA:11628) in the Rhea hierarchy (using rdfs:subClassOf+)
  18. Select all approved reactions with CHEBI:17815 (a 1,2-diacyl-sn-glycerol) or one of its descendant. Display the EC numbers if the rhea-ec link exists
  19. For a given protein (UniProt entry P15877), show its cofactor and the Rhea reaction(s) that modify the cofactor (federated query)